X Shirley Liu

X Shirley Liu

Professor of Biostatistics and Computational Biology
Dana-Farber Cancer Institute
Harvard T.H. Chan School of Public Health
X Shirley Liu

Dr. X Shirley Liu is Professor of Biostatistics and Computational Biology at the Department of Data Science at Dana-Farber Cancer Institute and Harvard University. She is also the director of Functional Cancer Epigenetic at the Dana-Farber Cancer Institute. Her work is focused on algorithm development and data integration modeling for translational cancer research. 


Her laboratory developed widely used algorithms and tools for transcription factor motif finding, ChIP-chip/seq, chromatin accessibility profiles, CRISPR screen analyses, and tumor immune characterization. She pioneered in using chromatin dynamics to predict trans-factors and cis-elements involved in biological processes and diseases. She also contributed to the discovery of drug response biomarkers, drug resistance mechanisms, and effective combination therapies.  

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